Resident Evil 0 Wiki
Classic Survival HorrorA complete Resident Evil 0 wiki covering characters, story, weapons, items, enemies, puzzles, walkthroughs, bosses, and gameplay mechanics.
Latest Updates
Resident Evil 0 Achievement Guide: Full Trophy Roadmap, Tips & Leech Hunter Strategy
Resident Evil 0 Beginner Guide: Partner Swaps, Item Drops, and Survival Tips
Resident Evil 0 Guide: Partner Zapping, Item Drops, and Every Major Boss
Resident Evil 0 Laboratory Walkthrough: Survive the Final Lab and Queen Leech Fight
Resident Evil 0 Trophy Guide: Platinum Roadmap, Hard Mode Tips, and Leech Hunter Help
Resident Evil 0 Walkthrough Train Guide: Every Car, Puzzle, and Boss on the Ecliptic Express
Resident Evil 0 Walkthrough: Complete Guide to the Train, Training Facility, and Final Boss
Resident Evil 0 Animal Puzzle Guide: Statues, Crests, and Creature-Themed Riddles
Start Here
Your Resident Evil 0 Journey
Beginner Guide
Learn partner zapping, the drop-anywhere item system, herb mixing, combat basics, and saving before you board the Ecliptic Express.
Character Roles
See what Rebecca Chambers and Billy Coen each do best, from herb mixing and puzzle items to heavy lifting and shotgun duty.
Partner Zapping & Inventory
Master the two-character swap, six-slot inventories, and the floor-drop storage that replaces item boxes in Resident Evil 0.
Boss & Combat Guide
Prep for the Leech humanoid, Infected bat, giant spider, Prototype Tyrant, and the two-phase final boss with the right weapons.
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Resident Evil 0 Achievement Guide: Full Trophy Roadmap, Tips & Leech Hunter Strategy
A complete Resident Evil 0 achievement guide: difficulty roadmap, Leech Hunter tips, Wesker Mode unlocks, and the fastest route to 100% completion.
Resident Evil 0 Beginner Guide: Partner Swaps, Item Drops, and Survival Tips
A practical Resident Evil 0 beginner guide covering the partner swap system, no item boxes, herb mixing, ammo discipline, and boss prep.
Resident Evil 0 Guide: Partner Zapping, Item Drops, and Every Major Boss
A complete Resident Evil 0 guide covering the Partner Zapping System, item dropping, herb mixing, boss strategies, and unlockables.
Resident Evil 0 Laboratory Walkthrough: Survive the Final Lab and Queen Leech Fight
A complete Resident Evil 0 laboratory walkthrough: prep checklist, stage-by-stage route, leech enemy tactics, the Tyrant prototype, and the Queen Leech.
Resident Evil 0 Trophy Guide: Platinum Roadmap, Hard Mode Tips, and Leech Hunter Help
A complete Resident Evil 0 trophy guide: platinum roadmap, Hard mode strategy, Leech Hunter cleanup, Wesker Mode, and speed-run routing tips.
Resident Evil 0 Walkthrough Train Guide: Every Car, Puzzle, and Boss on the Ecliptic Express
A Resident Evil 0 walkthrough train guide: car-by-car objectives, partner zapping tips, item management, and how to survive the Ecliptic Express.
Resident Evil 0 Walkthrough: Complete Guide to the Train, Training Facility, and Final Boss
A full Resident Evil 0 walkthrough covering the Ecliptic Express, partner swapping, item management, every boss fight, and all unlockables.
Resident Evil 0 Animal Puzzle Guide: Statues, Crests, and Creature-Themed Riddles
Solve every Resident Evil 0 animal puzzle: creature-themed statues, crests, and locks explained, with tips for Rebecca and Billy's toughest riddles.
Resident Evil 0 Chess Puzzle Guide: Solve the Chessboard Riddle Fast
Stuck on the Resident Evil 0 chess puzzle? Learn how the chessboard riddle works, how to prep Billy and Rebecca, and the mistakes that cost you runs.
Resident Evil 0 Clock Puzzle Guide: Clues, Steps, and Partner Tips
Stuck on the Resident Evil 0 clock puzzle? Get the clue-hunting method, step-by-step hand settings, partner zapping tips, and fixes for common mistakes.
Resident Evil 0 Puzzle Solutions: Every Major Brain-Teaser and How to Beat It
A complete walkthrough of Resident Evil 0 puzzle solutions, from the train's ring lock to lab valves, plus partner-swap tips that save time.
Resident Evil 0 Statue Puzzle Guide: Solve the Training Facility Statue Lock
Stuck on the Resident Evil 0 statue puzzle? Learn how the statue lock works, how to prep your partner, and the mistakes that force a long backtrack.
Resident Evil 0 Train Brake Code: How to Solve the Ecliptic Express Brake Puzzle
Stuck on the Ecliptic Express? Here's how the Resident Evil 0 train brake code puzzle works, what to collect first, and the mistakes that stall players.
Resident Evil 0 Water Treatment Plant Puzzle Guide: Valves, Water Levels, and Safe Routes
Stuck on the Resident Evil 0 water treatment plant puzzle? Learn the valve logic, item-drop strategy, and enemy routes that get you through fast.
Resident Evil 0 Herbs Guide: Every Mix, Combo, and Inventory Tip
Master Resident Evil 0 herbs: all green, red, and blue mix combos, who can combine them, and how to stash them with no item box.
Resident Evil 0 Hookshot Guide: Location, Uses, and Inventory Tips for Every Player
The Resident Evil 0 Hookshot is a must-carry key item. Learn where to find it, which gaps it solves, and how to manage its inventory cost.
Resident Evil 0 Ink Ribbon Guide: Save Smart, Carry Less, Survive Longer
Master the Resident Evil 0 ink ribbon system with save strategies, inventory tips, and difficulty breakdowns for Rebecca and Billy's prequel nightmare.
Resident Evil 0 Inventory Guide: Slots, Drops, and Partner Swaps Explained
Master the Resident Evil 0 inventory: six slots per character, no item boxes, and a drop system that turns every room into storage.
Resident Evil 0 Items Guide: Inventory, Herbs, and Key Item Tips
A complete guide to Resident Evil 0 items: how the drop-anywhere system works, which herbs to mix, weapon picks, key items, and inventory tips.
Resident Evil 0 Weapons Guide: Every Gun, Ammo Type, and Unlockable Ranked
A complete breakdown of Resident Evil 0 weapons: handguns, shotgun, grenade launcher, hunting gun, magnum, ammo types, and unlockables.
Resident Evil 0 Antagonist Guide: Dr. James Marcus, Queen Leech & Every Villain Explained
Meet every Resident Evil 0 antagonist — Dr. James Marcus, the Queen Leech, Wesker, Birkin, and the Proto Tyrant — with boss tips, lore, and a full roster.
Resident Evil 0 Billy Coen Explained: Backstory, Abilities, and His Unresolved Fate
Who is Billy Coen in Resident Evil 0? Explore his convict backstory, partner abilities, story ending, and why Capcom never brought him back.
Resident Evil 0 James Marcus: The Mad Scientist Behind the T-Virus Outbreak
A deep dive into Resident Evil 0 James Marcus — his leech experiments, his assassination, and the Queen Leech boss that brought him back.
Resident Evil 0 Protagonist Guide: Rebecca Chambers, Billy Coen, and Why Both Matter
Meet the Resident Evil 0 protagonist duo: Rebecca Chambers and Billy Coen. Their backstories, gameplay roles, and story impact explained in one guide.
Resident Evil 0 Rebecca Chambers Guide: Stats, Partner Tactics, and Survival Tips
A complete Resident Evil 0 Rebecca Chambers guide: her S.T.A.R.S. backstory, herb mixing skills, partner tactics with Billy Coen, and survival tips.
Resident Evil 0 Wesker Explained: Story Role, Wesker Mode, and Unlock Guide
Albert Wesker secretly drives Resident Evil 0's outbreak. Here's his story role, how Wesker Mode works in the HD remaster, and tips to unlock it fast.
Resident Evil 0 Difficulty Levels Explained: Easy, Normal, Hard & Wesker Mode
Compare all Resident Evil 0 difficulty levels — Easy, Normal, Hard, Wesker Mode, and Leech Hunter — with survival tips, rewards, and which mode to pick.
Resident Evil 0 Extra Game Modes: Leech Hunter, Wesker Mode & Unlockables
A complete guide to the Resident Evil 0 extra game content: how to unlock Leech Hunter and Wesker Mode, what they reward, and tips to clear them.
Resident Evil 0 Leech Hunter Guide: Leech Charms, Ranks, and Rewards Explained
A complete guide to Resident Evil 0 Leech Hunter: how to unlock the mode, collect all 100 leech charms, survive the Leech Man, and earn every reward.
Resident Evil 0 Leech Hunter Rewards: How to Unlock Every Bonus and Infinite Ammo
Resident Evil 0 Leech Hunter rewards explained: how the graded bonus system works, what a perfect 100-charm run unlocks, and tips to get there.
Resident Evil 0 Unlockables Guide: Leech Hunter, Wesker Mode, and Unlimited Ammo
Every Resident Evil 0 unlockable explained: unlock Leech Hunter, hit the 100-leech tier for unlimited ammo, and play Wesker Mode in the HD Remaster.
Resident Evil 0 Wesker Mode: Abilities, Unlock Guide, and Tips for the Bonus Campaign
Wesker Mode in Resident Evil 0 HD Remaster explained: how to unlock it, Wesker's dash and Gaze of Destruction, difficulty tips, and trophy advice.
Resident Evil 0 Ending Explained: Queen Leech, Billy's Fate, and the RE1 Setup
A full breakdown of the Resident Evil 0 ending: the Queen Leech final boss, the Tyrant escape, Billy Coen's fate, and the epilogue that leads into RE1.
Resident Evil 0 Lore Explained: The Train, the Leeches, and the Birth of the T-Virus
Dive into Resident Evil 0 lore: the Ecliptic Express, James Marcus, the leech queen, Billy Coen, and how the prequel sets up the entire series timeline.
Resident Evil 0 Story Explained: Rebecca, Billy, and the Ecliptic Express
A complete Resident Evil 0 story explained guide: the Ecliptic Express, Rebecca and Billy Coen, Marcus's leeches, and how the prequel sets up the mansion incident.
Resident Evil 0 Story Explained: Rebecca, Billy, and the Train That Started It All
A full breakdown of the Resident Evil 0 story: the Ecliptic Express, Rebecca and Billy, Dr. Marcus, and how the prequel sets up the mansion incident.
Resident Evil 0 Timeline Explained: Where the Prequel Fits in the Series
A complete Resident Evil 0 timeline breakdown — key dates, locations, characters, and exactly where the 1998 prequel fits in the series chronology.
Resident Evil 0 Achievement Guide: Full Trophy Roadmap, Tips & Leech Hunter Strategy
A complete Resident Evil 0 achievement guide: difficulty roadmap, Leech Hunter tips, Wesker Mode unlocks, and the fastest route to 100% completion.
Resident Evil 0 Beginner Guide: Partner Swaps, Item Drops, and Survival Tips
A practical Resident Evil 0 beginner guide covering the partner swap system, no item boxes, herb mixing, ammo discipline, and boss prep.
Resident Evil 0 Guide: Partner Zapping, Item Drops, and Every Major Boss
A complete Resident Evil 0 guide covering the Partner Zapping System, item dropping, herb mixing, boss strategies, and unlockables.
Resident Evil 0 Laboratory Walkthrough: Survive the Final Lab and Queen Leech Fight
A complete Resident Evil 0 laboratory walkthrough: prep checklist, stage-by-stage route, leech enemy tactics, the Tyrant prototype, and the Queen Leech.
Resident Evil 0 Trophy Guide: Platinum Roadmap, Hard Mode Tips, and Leech Hunter Help
A complete Resident Evil 0 trophy guide: platinum roadmap, Hard mode strategy, Leech Hunter cleanup, Wesker Mode, and speed-run routing tips.
Resident Evil 0 Walkthrough Train Guide: Every Car, Puzzle, and Boss on the Ecliptic Express
A Resident Evil 0 walkthrough train guide: car-by-car objectives, partner zapping tips, item management, and how to survive the Ecliptic Express.
Resident Evil 0 Walkthrough: Complete Guide to the Train, Training Facility, and Final Boss
A full Resident Evil 0 walkthrough covering the Ecliptic Express, partner swapping, item management, every boss fight, and all unlockables.
Resident Evil 0 Animal Puzzle Guide: Statues, Crests, and Creature-Themed Riddles
Solve every Resident Evil 0 animal puzzle: creature-themed statues, crests, and locks explained, with tips for Rebecca and Billy's toughest riddles.
Resident Evil 0 Chess Puzzle Guide: Solve the Chessboard Riddle Fast
Stuck on the Resident Evil 0 chess puzzle? Learn how the chessboard riddle works, how to prep Billy and Rebecca, and the mistakes that cost you runs.
Resident Evil 0 Clock Puzzle Guide: Clues, Steps, and Partner Tips
Stuck on the Resident Evil 0 clock puzzle? Get the clue-hunting method, step-by-step hand settings, partner zapping tips, and fixes for common mistakes.
Resident Evil 0 Puzzle Solutions: Every Major Brain-Teaser and How to Beat It
A complete walkthrough of Resident Evil 0 puzzle solutions, from the train's ring lock to lab valves, plus partner-swap tips that save time.
Resident Evil 0 Statue Puzzle Guide: Solve the Training Facility Statue Lock
Stuck on the Resident Evil 0 statue puzzle? Learn how the statue lock works, how to prep your partner, and the mistakes that force a long backtrack.
Resident Evil 0 Train Brake Code: How to Solve the Ecliptic Express Brake Puzzle
Stuck on the Ecliptic Express? Here's how the Resident Evil 0 train brake code puzzle works, what to collect first, and the mistakes that stall players.
Resident Evil 0 Water Treatment Plant Puzzle Guide: Valves, Water Levels, and Safe Routes
Stuck on the Resident Evil 0 water treatment plant puzzle? Learn the valve logic, item-drop strategy, and enemy routes that get you through fast.
Resident Evil 0 Herbs Guide: Every Mix, Combo, and Inventory Tip
Master Resident Evil 0 herbs: all green, red, and blue mix combos, who can combine them, and how to stash them with no item box.
Resident Evil 0 Hookshot Guide: Location, Uses, and Inventory Tips for Every Player
The Resident Evil 0 Hookshot is a must-carry key item. Learn where to find it, which gaps it solves, and how to manage its inventory cost.
Resident Evil 0 Ink Ribbon Guide: Save Smart, Carry Less, Survive Longer
Master the Resident Evil 0 ink ribbon system with save strategies, inventory tips, and difficulty breakdowns for Rebecca and Billy's prequel nightmare.
Resident Evil 0 Inventory Guide: Slots, Drops, and Partner Swaps Explained
Master the Resident Evil 0 inventory: six slots per character, no item boxes, and a drop system that turns every room into storage.
Resident Evil 0 Items Guide: Inventory, Herbs, and Key Item Tips
A complete guide to Resident Evil 0 items: how the drop-anywhere system works, which herbs to mix, weapon picks, key items, and inventory tips.
Resident Evil 0 Weapons Guide: Every Gun, Ammo Type, and Unlockable Ranked
A complete breakdown of Resident Evil 0 weapons: handguns, shotgun, grenade launcher, hunting gun, magnum, ammo types, and unlockables.
Resident Evil 0 Antagonist Guide: Dr. James Marcus, Queen Leech & Every Villain Explained
Meet every Resident Evil 0 antagonist — Dr. James Marcus, the Queen Leech, Wesker, Birkin, and the Proto Tyrant — with boss tips, lore, and a full roster.
Resident Evil 0 Billy Coen Explained: Backstory, Abilities, and His Unresolved Fate
Who is Billy Coen in Resident Evil 0? Explore his convict backstory, partner abilities, story ending, and why Capcom never brought him back.
Resident Evil 0 James Marcus: The Mad Scientist Behind the T-Virus Outbreak
A deep dive into Resident Evil 0 James Marcus — his leech experiments, his assassination, and the Queen Leech boss that brought him back.
Resident Evil 0 Protagonist Guide: Rebecca Chambers, Billy Coen, and Why Both Matter
Meet the Resident Evil 0 protagonist duo: Rebecca Chambers and Billy Coen. Their backstories, gameplay roles, and story impact explained in one guide.
Resident Evil 0 Rebecca Chambers Guide: Stats, Partner Tactics, and Survival Tips
A complete Resident Evil 0 Rebecca Chambers guide: her S.T.A.R.S. backstory, herb mixing skills, partner tactics with Billy Coen, and survival tips.
Resident Evil 0 Wesker Explained: Story Role, Wesker Mode, and Unlock Guide
Albert Wesker secretly drives Resident Evil 0's outbreak. Here's his story role, how Wesker Mode works in the HD remaster, and tips to unlock it fast.
Resident Evil 0 Difficulty Levels Explained: Easy, Normal, Hard & Wesker Mode
Compare all Resident Evil 0 difficulty levels — Easy, Normal, Hard, Wesker Mode, and Leech Hunter — with survival tips, rewards, and which mode to pick.
Resident Evil 0 Extra Game Modes: Leech Hunter, Wesker Mode & Unlockables
A complete guide to the Resident Evil 0 extra game content: how to unlock Leech Hunter and Wesker Mode, what they reward, and tips to clear them.
Resident Evil 0 Leech Hunter Guide: Leech Charms, Ranks, and Rewards Explained
A complete guide to Resident Evil 0 Leech Hunter: how to unlock the mode, collect all 100 leech charms, survive the Leech Man, and earn every reward.
Resident Evil 0 Leech Hunter Rewards: How to Unlock Every Bonus and Infinite Ammo
Resident Evil 0 Leech Hunter rewards explained: how the graded bonus system works, what a perfect 100-charm run unlocks, and tips to get there.
Resident Evil 0 Unlockables Guide: Leech Hunter, Wesker Mode, and Unlimited Ammo
Every Resident Evil 0 unlockable explained: unlock Leech Hunter, hit the 100-leech tier for unlimited ammo, and play Wesker Mode in the HD Remaster.
Resident Evil 0 Wesker Mode: Abilities, Unlock Guide, and Tips for the Bonus Campaign
Wesker Mode in Resident Evil 0 HD Remaster explained: how to unlock it, Wesker's dash and Gaze of Destruction, difficulty tips, and trophy advice.
Resident Evil 0 Ending Explained: Queen Leech, Billy's Fate, and the RE1 Setup
A full breakdown of the Resident Evil 0 ending: the Queen Leech final boss, the Tyrant escape, Billy Coen's fate, and the epilogue that leads into RE1.
Resident Evil 0 Lore Explained: The Train, the Leeches, and the Birth of the T-Virus
Dive into Resident Evil 0 lore: the Ecliptic Express, James Marcus, the leech queen, Billy Coen, and how the prequel sets up the entire series timeline.
Resident Evil 0 Story Explained: Rebecca, Billy, and the Ecliptic Express
A complete Resident Evil 0 story explained guide: the Ecliptic Express, Rebecca and Billy Coen, Marcus's leeches, and how the prequel sets up the mansion incident.
Resident Evil 0 Story Explained: Rebecca, Billy, and the Train That Started It All
A full breakdown of the Resident Evil 0 story: the Ecliptic Express, Rebecca and Billy, Dr. Marcus, and how the prequel sets up the mansion incident.
Resident Evil 0 Timeline Explained: Where the Prequel Fits in the Series
A complete Resident Evil 0 timeline breakdown — key dates, locations, characters, and exactly where the 1998 prequel fits in the series chronology.
What is Resident Evil 0?
Resident Evil 0 is a survival horror game from Capcom and a prequel to the original Resident Evil. Set in 1998, it follows S.T.A.R.S. medic Rebecca Chambers and escaped convict Billy Coen as they uncover the truth behind the Umbrella Corporation's experiments.
The HD Remaster modernizes the classic experience with updated visuals, widescreen support, and additional content such as Wesker Mode. Our wiki covers every area, puzzle, weapon, and boss with detailed guides and reference tables.
Explore All GuidesDeveloper
Capcom
Platform
PC, PlayStation, Xbox, Nintendo
Genre
Survival Horror
Original Release
2002
Playable Characters
Rebecca & Billy
Main Campaign
1
Bonus Mode
Wesker Mode
Explore the Resident Evil 0 Wiki
Master Resident Evil 0 with essential walkthroughs, character and weapon references, puzzle solutions, boss strategies, and completionist guides.
Resident Evil 0 Beginner Guide
An accessible starting guide covering partner zapping, the no-item-box inventory, herb mixing, combat basics, saving, and survival tips.
Resident Evil 0 Walkthrough
A complete route through the Ecliptic Express, training facility, and underground laboratory with key objectives, items, and boss encounters.
Resident Evil 0 Characters
Introduces Rebecca Chambers and Billy Coen, their different gameplay roles, and when character switching matters most.
Resident Evil 0 Weapons and Items
A practical reference for weapons, ammunition, healing items, key items, and inventory management without item boxes.
HandgunCommon ammo and the baseline weapon for clearing roomsShotgunClose-range crowd control, best carried by BillyMagnumRare boss killer; save it for the Prototype TyrantHookshotKey item and traversal tool; losing it stalls the mid-gameResident Evil 0 Puzzle Guide
Every important puzzle solution with the required items, switches, combinations, and character interactions.
Resident Evil 0 Boss Guide
Tactics, recommended weapons, positioning, and resource management for every major boss encounter.
Prototype Tyrant: save magnum and grenade rounds, then punish the charge
Final boss Queen Leech: two-phase fight, bring maximum healing
Infected bat: dodge the swoops and unload during landing windows
Leech humanoid: keep your distance, circle, and use handgun or shotgun
Resident Evil 0 Achievements
Every achievement and trophy with concise requirements to help completionists unlock them all.
Resident Evil 0 Wesker Mode
How the HD Remaster's Wesker Mode differs from the standard campaign, including abilities and practical tips.
Frequently Asked Questions
Quick answers to the most common questions about Resident Evil 0.
Ready to Master Resident Evil 0?
From the Ecliptic Express to the laboratory, our community wiki covers every puzzle, boss, weapon, and secret in Resident Evil 0.